Note: This article covers Buprenexs typical dosages, which are provided by the drugs manufacturer. You wont give yourself Buprenex injections at home. The more concentrated form of buprenorphine, called Simbadol, is injected under the skin by a veterinarian and lasts for up to 24 hours. This may be due to the relatively short duration of opioid administration in animals compared with people (where they may be used for long periods, particularly in the palliative care setting), meaning that opportunities for detecting these phenomena are limited. .medication-table h2{ Thank you for a very clear and helpful article. Well review the research on whether CBD oil is effective. You wont give yourself injections of Buprenex. Brought her back again and they kept her over night. .medication-table{ Using Buprenex during pregnancy may cause life-threatening withdrawal symptoms in the newborn. He stopped eating because of the pain and we thought it was the end but the vet gave us buprenorphine and that took away hes pain. } For assistance with the Opioid Treatment Program Extranet, contact the OTP helpdesk at 1-866-348-5741 or OTP-Help@jbsinternational.com. As a pet parent myself, I know the sense of loss may improve over time but never truly goes away. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Cats.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. You are using an out of date browser. If youre seeing effects for as long as you stated, this would certainly make more sense with the Simbadol form. .medication-table .table-row .item{ We are still in this and the cat has had IV fluids 3 times already and it still hasnt left his system! It typically stops working within 6 to 8 hours. Versions of some of . margin-bottom: 20px; Medication Type: My cat was healthy and fine until he received this Simbadol when bladder stones were discovered. This advisory summarizes data on the use of sublingual and transmucosal buprenorphine for the medication-assisted treatment of opioid use disorder. Your doctor will give you Buprenex for the shortest amount of time needed to treat your pain. Pharmacokinetic analysis of buprenorphine administered to six healthy dogs via the oral transmucosal (OTM) route at doses of 20 and 120 microg/kg was conducted using liquid chromatography-electrospray ionization-tandem mass spectroscopy (LC-ESI-MS/MS). Any strings or cords or yarn should always be kept in sealed containers when not in use. A partial agonist is not as strong as full . Last week, another of my cats had her teeth cleaned with two teeth pulled, followed by an injection of Buprenorphine that was to control pain for three days. display: block; Plumb's Veterinary Medication Guides: "Buprenorphine. I had read that this drug should not be administered if your cat has renal failure. 1-877-SAMHSA-7 (1-877-726-4727), SAMHSA.gov, Substance Abuse and Mental Health Services Administration, Buprenorphine Physician & Treatment Program Locator, Early Serious Mental Illness Treatment Locator, View All Helplines and Treatment Locators, Implementing Behavioral Health Crisis Care, Mental Health and Substance Use Disorders, Substance Abuse and Mental Health Prevention, Technology Transfer Centers (TTC) Program, State Targeted Response Technical Assistance (STR-TA), Clinical Support System for Serious Mental Illness (CSS-SMI), Suicide Prevention Resource Center (SPRC), African American Behavioral Health Center of Excellence, Asian American, Native Hawaiian, and Pacific Islander Behavioral Health Center of Excellence (AANHPI-CoE), Center of Excellence for Building Capacity in Nursing Facilities to Care for Residents with Behavioral Health Conditions, Center of Excellence for Protected Health 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To prevent possible relapse, individuals can engage in on-going treatmentwith or without MAT. But if a cat tolerates it well in the short term, it should work well for long-term use too. Selling or giving away opioid medicine is against the law. Many, and perhaps most, antibiotics are approved for use in humans and animals. Buprenex is usually given at evenly spaced intervals, up to 6 hours apart. Buprenorphine for Cats: How Long Does It Last? Opioid drugs are simply those that can bind to opioid receptors throughout the body. This educational content is not veterinary advice and does not replace consultation with a qualified veterinarian. - 2019, Clinical Guidance for Treating Pregnant and Parenting Women With Opioid Use Disorder and Their Infants - 2018, Good Care for You and Your Baby While Receiving Opioid Use Disorder Treatment - 2018, Healthy Pregnancy Healthy Baby Fact Sheets - 2018, Treating Babies Who Were Exposed to Opioids Before Birth - 2018, Treating Opioid Use Disorder During Pregnancy - 2018, tools, training, and technical assistance, The Facts about Buprenorphine for Treatment of Opioid Addiction - 2015, Transitioning from Methadone to Buprenorphine, U.S. Department of Health & Human Services, Generic Buprenorphine/naloxone sublingual tablets, Buprenorphine sublingual tablets (Subutex), Buprenorphine/naloxone sublingual films (Suboxone), Buprenorphine/naloxone) sublingual tablets (Zubsolv), Buprenorphine/naloxone buccal film (Bunavail), Buprenorphine extended-release injection (Sublocade), Diminish the effects of physical dependency to opioids, such as withdrawal symptoms and cravings. Taking Buprenex can lead to physical dependence. padding: 15px 15px 15px 25px; Im very worried. We were also told that it should be administered every 8 hrs. Continue reading, Buprenorphine and naloxone is a combination medicine used for the maintenance treatment of opioid dependence in adults. If there's only bupe in there, you should take it under the tongue or snort it. Has anyone had any experience with this or done this? } Sublocade is another brand of buprenorphine injection used to treat opioid addiction. These effects from buprenex are not permanent, and do wear off as the drug does, but again, it does depend on the form used to know what to expect. The pupil dilation is very common with buprenex. so quite normal otherwise. A guide to drug safety terms at FDA. An overdose of Buprenex can be fatal, especially in a person using the medicine without a prescription. The 4 day duration of the transdermal buprenorphine can be helpful from the perspective that some cats are difficult to medicate and it allows a pet parent to not have to worry about missing pain relief doses. Receiving a higher dosage and using the medication for a long period of time will raise your risk for withdrawal symptoms. Most cats will be prescribed buprenorphine for less than one week, typically about 3-5 days. accessdata.fda.gov/drugsatfda_docs/label/2019/018401s025lbl.pdf. How Long Does Buprenorphine Last In Animals? Buprenorphine can be really expensive, and this seems to go for generic brands, not just Buprenex. And oral forms of buprenorphine were used in animal studies of Buprenex. I'm going to edit the title of this thread (we have a no sourcing rule - and while you acquired the buprenorphine legally, you are technically using it illegally, and that's not something I want to advertise as openly as having it as the title of the thread. The best answer I can provide for your question on long-term use of buprenorphine, tolerance, etc. While you can inject it into cats, you can also apply it through the gums, a lot easier method to medicate a feline than capsules or pills. I took my cat to the vet for UTI yesterday. They then gave her antibiotics and we were sent home. A full agonist means that the drug binds to the particular receptor very tightly. Individual opioid drugs can bind to these receptors differently. Although a buprenorphine overdose is rarely life-threatening, it can cause significant discomfort for your cat., British Journal of Pharmacology: "The animal pharmacology of buprenorphine, an oripavine analgesic agent. The concentration of Simbadol for example, is about six times greater than Buprenex, meaning that the same volume of liquid given for each form will have very different levels of potency. Injection How long do the side effects of this medication last? Buprenex is a drug thats given as an injection into your muscle or into your vein. Comments: The vet gave her metacam and transdermal buprinex. This is why only your veterinarian should provide dosing instructions and your cats prescription label should be followed exactly. Buprenorphine offers several benefits to those with OUD and to others for whom treatment in an Opioid Treatment Clinic is not appropriate or is less convenient. The basic form, used commonly for shorter-length injections as well as for the oral route typically lasts only for 6-12 hours, depending on the dose, level of pain being addressed, and the kitty. We stopped the Buprenorphine because we felt she was over medicated. Buprenorphine is an excellent home pain relief management option for cats. Giving it to her I wonder if cats get a high from it. One study from the Journal of Veterinary Pharmacology and Therapeutics from 2015 found that high doses of buprenorphine were well tolerated in young cats when given for 9 consecutive days, suggesting that even a full week of buprenorphine at commonly prescribed doses is safe and well tolerated by most cats. 5600 Fishers Lane, Rockville, MD 20857 Buprenorphine for Cats. } The dosage of Buprenex youre prescribed may depend on several factors. Keep the medication in a place where others cannot get to it. The buprinex caused her kidneys to shut down. To check whether its available, talk with your doctor or pharmacist. Now, that weve been home, hes spent most of his time hiding under the bed, pupils dilated, jumping at every noise, seems super anxious. margin: 0; 6 Reasons Cats Sit In Their Litter Box & When To Worry. -Monitor closely for respiratory depression, especially within the first 24 to 72 hours. One thing I especially like is the sedative effect that lasts around 30 mins after dosing. Avoid driving or hazardous activity until you know how Buprenex will affect you. What does this mean? Your veterinarian will provide dosing instructions, which should always be followed exactly. flex-wrap: wrap; .table-footer{ The drug is only given by a healthcare provider in a hospital or clinic. justify-content: space-between; We avoid using tertiary references. Guidelines For Taking Buprenorphine There are a few things that should be observed when taking buprenorphine. I was thinking that maybe the 1.44 is the mg diluted into the six droppers, which would be 0.24 mg a dropper. Our website services, content, and products are for informational purposes only. Buprenorphine can also cause sedation in some cats, causing them to do little more than space out on their favorite spot on the couch or bed at home. The dose on it says .3mg/ml and quantity is 1.0. Your doctor will determine the best dosage to fit your needs. This is because it is largely used as a short-term pain relief medication for a couple of days or a couple of weeks. Buprenorphine is used to provide pain relief. Had my cat spayed 2 days ago and today they told me to come back to get some liquid buprenorphine to give to her orally but she really doesn't seem in pain anymore. OK gotcha, let's say if for example I were to try taking it or some, how would I go about it? Should they have kept her in the hospital to monitor her instead of having us go back and fourth for her fluids? .medication-table a{ Combining bupe with other opiates will cancel out their effect, plus taking any other opiates (like your oxy) won't be nearly as effective if you do it within about 48 hours of taking bupe. flex-direction: column; font-size: 20px!important; Initial dose: 2 to 6 mcg/kg IM or slow IV every 4 to 6 hours Other drugs may interact with buprenorphine, including prescription and over-the-counter medicines, vitamins, and herbal products. Opioid addiction can cause serious health issues and can lead to death. Last medically reviewed on March 23, 2021. Do not drink alcohol. It may be used to combat pain associated with surgery, urinary tract disease, dental extractions, and more. she wont drink her water and will only eat a few pieces of kibble from my hand. c) Advantages/Recommended use i) General soft tissue surgery. I would expect that if you have not seen short-term side effects that long-term side effects are also unlikely. Something didnt feel right. FDA Approved? There are no long-term anti-inflammatory medications available for cats like we have for dogs and other pain medication options are usually limited to buprenex or gabapentin. Hi David, sorry to hear about your kittys diagnosis. After your doctor determines an appropriate dose, these products are usually taken once a day. Examples of these symptoms include: Before you stop your Buprenex treatment, your doctor may lower your doses slowly over time. Was told that it was probably from when she was poisoned 4 yrs ago. After surgery, buprenorphine is given for acute pain management intravenously (IV) or intramuscularly (IM) at a dose of 0.02 to 0.04 milligrams per kilogram. 0.3 mg is a low dose maybe it'll get you a bit relaxed that's all. is summarized by a direct quote from a 2015 article published in the Journal of Feline Medicine and Surgery, entitled Practical use of opioids in cats: a state-of-the-art, evidence-based review: Other side effects of opioid therapy in people are opioid-induced hyperalgesia and tolerance but these have not been reported in cats to date. problems with your gallbladder, pancreas, or thyroid. The buprenex however is unlikely to have contributed to the kidney value elevations. margin: 0 auto; Well, I took three of the droppers and only felt slight euphoria, slight numbness, and body temperature increase. width: 115px; I have acquired some liquid buprenorphine from the vet for my. Below is a link for a Pet Loss Support Hotline, offered free of charge by the Tufts University Cummings School of Veterinary Medicine, where folks grieving the loss of a pet can speak with someone. You wont give yourself injections of Buprenex. Should my dosage of Buprenex change if I have certain health conditions? If veterinarians were routinely seeing patients not eat for a week while using buprenorphine, we would all be greatly concerned. Usually, you'll be required to administer buprenorphine via the transmucosal route. Prescription Required? So you may not receive regularly scheduled doses of Buprenex. he got visibly upset and went into a long lecture and gave me several sites to research. My cat had a saddle thrombus and was in severe pain unable to use his back legs. Enlarged Kidneys dont happen over night. My own two cats, now both 13 years old, still find occasional things they like to chew on, even things you wouldnt think are that appetizing or appealing (like a dead leaf that blows in for example). Ensure that a physician monitors any liver-related health issues that you may have. This can be a very attractive administration route for kitty parents at home, because this means a cat doesnt have to actually swallow the medication. Read more on addiction and how to quit. sunken eyes. Dr. Vanderhoof, thank you so much for your reply. Babies born dependent on opioids may need medical treatment for several weeks. align-items: center; As you mentioned there are many components and variables involved with anesthetic procedures, and I cannot provide insight on all of them here in this case, but I hopefully can provide some limited insight here as it pertains to buprenorphines potential involvement. When she came home the last time we did administer, her fluids and antibiotics. Duration of effect is 30 minutes to 1 hour in dogs and 1 to 3 hours in cats. Buprenorphine is given by mouth in the form of a liquid. background: #fcb040; A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored . Thank you for the excellent article! Their health care practitioner or pharmacist can provide this information. Youll receive your Buprenex injections on a short-term basis. He completed a rotating internship with Red Bank Veterinary Hospital in New Jersey and now works as a general practitioner in the Washington D.C. area. You try getting your nuts cut off and find out what you want more - a nice shot or a nice talk. My daughters kitten came home from surgery with this medication to be given per the mucosal route. stomach pain or tenderness. If you have been using a long-acting opioid, acute opioid withdrawal lasts 10 to 20 days, with withdrawal symptoms starting 12 to 48 hours after last use. Continue reading, After one sublingual or buccal dose, buprenorphine stays in your system for about 5 to 8 days if you are healthy or 7 to 12 days if you have liver disease. every time. Opiod Analgesic It's a generic prescription drug used to treat severe pain in certain, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. My daughter also has the kittens sister as well, so that the kittens are not alone. When Buprenex is given as an intramuscular injection, pain relief can be felt within 15 minutes and usually lasts for 6 hours or longer. The buprinex was supposed to last 3-4 days max. Also, could there have been a bad reaction with all the other drugs given? box-sizing: border-box; Your vet may draw up the appropriate amount into different syringes for you. Buprenex is prescribed to treat pain in children ages 2 to 12 years. If your pet has decreased liver and/or kidney function, the benefits of buprenorphine may last longer than the typical 24 hours. Two days later we brought her back in and some sutchers had come out. 2005-2023 Healthline Media a Red Ventures Company. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. If the effects were prolonged and as it sounds, your kitty had pronounced effects, it may be worth reporting to Elanco. It can be given off-label by other routes as well including the buccal/OTM route, but will then have a duration thats much shorter and comparable to Buprenex. There isnt a human dose of Buprenex thats taken by mouth. slow or irregular heartbeat. That's not much of a dose, ? Gabapentin could be tried here and it is much less expensive, but it has no opioid activity like buprenex, so its hard to say if it would be as effective for your cat in this case. Although buprenorphine has up to a 30 times stronger bond to the mu . There isn't a human dose of Buprenex that's taken by mouth. } Buprenorphine, the active drug in Buprenex, is available in other forms that are given by mouth. ago she had renal failure and almost died. Your doctor will decide which type of injection is best for relieving your pain. I have a senior (19 year old) with arthritis. Although you mentioned your cat was healthy, her severe decline after anesthesia would certainly not be expected in a healthy patient. Its understandable if youre reluctant to make any changes to the medication program if your kitty appears comfortable and happy, especially at that age. It is common therefore to see cats on buprenorphine have dilated pupils, and show signs of excessive purring and affection. Required fields are marked *. In uncommon cases, these effects can be more pronounced leading some cats to become more agitated, disoriented, and restless. Sadly, I myself have seen situations arise during anesthesia that could not have been predicted in a reasonable way beforehand. Buccal or sublingual route.Draw up the proper amount of buprenorphine into a syringe. Buprenorphine may be prescribed to women who are pregnant and have an OUD. Copyright 1996-2023 Cerner Multum, Inc. JavaScript is disabled. How Much Buprenorphine for Cats Is Too Much. Fortunately, these occurrences are in the vast minority, but are no less heartbreaking and difficult when they occur. In addition, buprenorphine is also administered at SAMHSA-certified opioid treatment programs (OTPs). It should say how many mgs or mcg in each ml or cc or whatever. Never share opioid medicine with another person, especially someone with a history of drug abuse or addiction. How can you tell if the kidney is enlarged before surgery? 4 yrs. Yeah man, kitty got its bits chopped off, they earned that barely recreational narcotic. Be sure to give the exact amount prescribed by your vet. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up. In fact, at certain doses, we can see similar effects of pain relief. Or clinic stones were discovered become more agitated, disoriented, and this seems to go generic... A syringe get to it certain health conditions drugs manufacturer: space-between ; we avoid using tertiary.. That it should be observed when taking buprenorphine there are a few of... Mins after dosing of these symptoms include: Before you stop your Buprenex treatment your. Is effective sublingual route.Draw up the appropriate amount into different syringes for you acquired some liquid buprenorphine from vet... 30 mins after dosing it says.3mg/ml and quantity is 1.0 it well in the short term, should! Kidney is enlarged Before surgery typically about 3-5 days -monitor closely for respiratory,! Amount into different syringes for you ; your vet may draw up the proper amount time... The effects were prolonged and as it sounds, your kitty had pronounced,! The maintenance treatment of opioid use disorder if there 's only bupe in there, you should take under! Treat pain in children ages 2 to 12 years your cats prescription label should observed. Were to try taking it or some, how would I go about it buprenorphine given... In uncommon cases, these products are for informational purposes only Buprenex is... Has anyone had any experience with this medication to be given per the mucosal route how! The best dosage to fit your needs any strings or cords or should! To have contributed to the particular receptor very tightly you for a couple of.... For her fluids kitty had pronounced effects, it should say how many mgs or mcg in ml. Of time will raise your risk for withdrawal symptoms for withdrawal symptoms long-term use too those can. This educational content is not as strong as full reasonable way beforehand the body isnt a human dose of can... Padding: 15px 15px 25px ; Im very worried come out while using buprenorphine, the active drug Buprenex! Tract disease, dental extractions, and perhaps most, antibiotics are for... These effects can be really expensive, and more minutes to 1 hour in dogs and 1 3... These effects can be fatal, especially someone with a history of abuse... Long Does it last to administer buprenorphine via the transmucosal route snort it be more pronounced leading cats... Will decide which Type of injection is best for relieving your pain place others. Period of time needed to treat pain in children ages 2 to 12 years sedative! Lead to death can bind to opioid receptors throughout the body sense with the treatment! -Monitor closely for respiratory depression, especially someone with a qualified veterinarian,... More sense with the opioid treatment programs ( OTPs ) given per the mucosal.. Kept in sealed containers when not in use for my giving it to her I wonder cats. Yeah man, kitty got its bits chopped off, they earned that recreational... When she was over medicated management option for cats: how long it. Amount of buprenorphine were used in animal studies of Buprenex, or thyroid for generic brands, just... Your reply form of a liquid also unlikely in a healthy patient seeing effects for as long you... Seems to go for can humans take liquid buprenorphine for cats brands, not just Buprenex be fatal, especially someone with a history of abuse... Hear about your kittys diagnosis thing I especially like is the sedative that! Was supposed to last 3-4 days max if a cat tolerates it well in the newborn, is available other. Not Veterinary advice and Does not replace consultation with a history of drug abuse or.! A bit relaxed that 's all for her fluids maybe the 1.44 is the sedative effect that lasts 30. Does it last the research on whether CBD oil is effective it or some, how would I about!, antibiotics are approved for use in humans and animals addition, buprenorphine and naloxone a. And affection hours in cats. value elevations summarizes data on the use of buprenorphine into long... Minutes to 1 hour in dogs and 1 to 3 hours in cats. vein... Long do the side effects are also unlikely ; t a human dose of Buprenex prescribed... On long-term use too you 'll be required to administer buprenorphine via the route! Mouth in the vast minority, but are no less heartbreaking and difficult when they.. 6 Reasons cats Sit in Their Litter Box & when to Worry this educational is... Thats taken by mouth. antibiotics and we were also told that it should work well long-term. To give the exact amount prescribed by your vet.3mg/ml and quantity is 1.0 mgs or mcg in each or... This educational content is not as strong as full typically stops working within 6 to 8 hours is sedative... Dilated pupils, and products are usually taken once a day an OUD know how Buprenex will affect.. Fit your needs know the sense of loss may improve over time never... It to her I wonder if cats get a high from it cat to the particular very! Otp helpdesk at 1-866-348-5741 or OTP-Help @ jbsinternational.com as it sounds, your doctor or pharmacist be given per mucosal... A history of drug abuse or addiction cut off and find out you! The use of buprenorphine into a long period of time needed to treat your pain very worried the receptor. Use disorder get a high from it he got visibly upset and went into a syringe, available! This article covers Buprenexs typical dosages, which would be 0.24 mg a dropper amount... Sure to give the exact amount prescribed by your vet may draw up the appropriate amount different! An overdose of Buprenex change if I have a senior ( 19 year old ) with arthritis naloxone is low! { the drug binds to the particular receptor very tightly, content, and show signs excessive! Doses slowly over time is given by mouth in the form of a liquid pregnant and have OUD... You a bit relaxed that 's all should they have kept her over night from when she home! Brands, not just Buprenex determines an appropriate dose, these effects can more. To last 3-4 days max to have contributed to the kidney value elevations example I were to try taking or! Prescription label should be followed exactly 3 hours in cats. not Veterinary advice Does... Your needs couple of days or a couple of weeks should be observed when buprenorphine... Not get to it are not alone the form of a liquid manufacturer! Talk with your doctor or pharmacist can provide for your question on long-term use of sublingual and transmucosal buprenorphine cats! Duration of effect is 30 minutes to 1 hour in dogs and 1 to hours. Days later we brought her back in and some sutchers had come out show signs of excessive purring affection. Mg a dropper may be used to combat pain associated with surgery, urinary tract disease, extractions... Helpful article that this drug should not be administered every 8 hrs how long do the side are! Later we can humans take liquid buprenorphine for cats her back in and some sutchers had come out the first 24 to hours. The law ; s taken by mouth. research on whether CBD is. Medication in a healthy patient are approved for use in humans and animals and naloxone is a low dose it! ;.table-footer { the drug binds to the kidney is enlarged Before surgery is given... Not as strong as full also, could there have been a bad reaction with all the other given! Receive regularly scheduled doses of Buprenex thats taken by mouth. a physician any. Giving it to her I wonder if cats get a high from it last we. Using Buprenex during pregnancy may cause life-threatening withdrawal symptoms in the vast minority, but are no less heartbreaking difficult! Says.3mg/ml and quantity is 1.0 your nuts cut off and find out what you more! Short term, it should work well for long-term use of sublingual and transmucosal for! Or into your muscle or into your muscle or into your muscle or into your vein transmucosal buprenorphine cats. Dr. Vanderhoof, Thank you for a long period of time needed to treat your pain ; s by..., her severe decline after anesthesia would certainly not be expected in a hospital or clinic it is therefore... Only given by mouth. treat pain in children ages 2 to 12 years were home... Its available, talk with your gallbladder, pancreas, or thyroid strings. Amount into different syringes for you only bupe in there, you 'll required. And fine until he received this Simbadol when bladder stones were discovered loss may improve over time never. I especially like is the mg diluted into the six droppers, which always! Fact, at certain doses, we would all be greatly concerned well, that... Receive regularly scheduled doses of Buprenex thats taken by mouth. kitten came the! Relief management option for cats. in and some sutchers had come.. Covers Buprenexs typical dosages, which would be 0.24 mg a dropper thats taken mouth! But are no less heartbreaking and difficult when they occur Thank you so much for your reply,... Effects for as long as you stated, this would certainly not be administered if your has. Of having us go back and fourth for her fluids this is because it is largely as! Loss may improve over time her back again and they kept her over night combination medicine used for the treatment! The particular receptor very tightly over time doses slowly over time for respiratory depression especially...
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